.Willis Group
 

Publications

Michael Willis - Publications


(123) “A copper(I)-catalyzed addition/annulation sequence for the two-component synthesis of γ-ylidenebutenolides”, Sangwon Seo and Michael C. Willis, Org. Lett. 2017, 19, 4556–4559 (doi: 10.1021/acs.orglett.7b02151).


(122) “Exploiting carbonyl groups to control intermolecular rhodium-catalyzed alkene and alkyne hydroacylation”, Thomas J. Coxon, Maitane Fernández, James Barwick-Silk, Alasdair I. McKay, Louisa E. Britton, Andrew S. Weller and Michael C. Willis, J. Am. Chem. Soc. 2017, 139, 10142–10149. (doi: 10.1021/jacs.7b05713)


(121) “Enantioselective three-component assembly of beta’-aryl-enones using a rhodium-catalyzed alkyne hydroacylation/aryl boronic acid conjugate addition sequence”, Ming Gao and Michael C. Willis, Org. Lett. 2017, 19, 2734–2737 (doi: 10.1021/acs.orglett.7b01087)


(120) “Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides”, Tim Markovic, Benjamin N. Rocke, David C. Blakemore, Vincent Mascitti and Michael C. Willis, Chem. Sci. 2017, 8, 4437-4442. (doi: 10.1039/C7SC00675F)


(119) “Copper(I)-catalyzed sulfonylative Suzuki-Miyaura cross-coupling”, Yiding Chen and Michael C. Willis, Chem. Sci. 2017, 8, 3249–3253. (doi: 10.1039/c6sc05483h)


(118) “Toolbox study for application of hydrogen peroxide as a versatile, safe and industrially-relevant green oxidant in continuous flow mode ”, Benjamin Martin,* Joerg Sedelmeier, Anaïs Bouisseau, Patricia Fernandez-Rodriguez, Julien Haber, Florian Kleinbeck, Sonja Kamptmann, Flavien Susanne, Pascale Hoehn, Marian Lanz, Laurent Pellegatti, Francesco Venturoni, Jeremy Robertson, Michael C. Willis and Berthold Schenkel, Green Chem. 2017, 19, 1439–1448 (doi: 10.1039/C6GC02899C).


(116) “One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides”, Alyn T. Davies, John M. Curto, Scott W. Bagley, and Michael C. Willis, Chem. Sci. 2017, 8, 1233-1237. (doi: 10.1039/C6SC03924C)


(116) “Sequential catalysis: Exploiting a single rhodium(I) catalyst to promote an alkyne hydroacylation–aryl boronic acid conjugate addition sequence” Maitane Fernández, Matthias Castaing and Michael C. Willis, Chem. Sci. 2017, 8, 536-540. (doi. 10.1039/C6SC03066A)


(115) “Two-component assembly of thiochroman-4-ones and tetrahydrothiopyran-4-ones using a rhodium-catalyzed alkyne hydroacylation/thio-conjugate-addition sequence”, Anaïs Bouisseau, John Glancy and Michael C. Willis, Org. Lett. 2016, 18, 5676–5679 (doi: 10.1021/acs.orglett.6b02909)


(114) “Traceless rhodium-catalyzed hydroacylation using alkyl aldehydes: The enantioselective synthesis of beta-aryl ketones”, Anaïs Bouisseau, Ming Gao and Michael C. Willis, Chem. Eur. J. 2016, 22, 15624–15628 (doi: 10.1002/chem.201604035)


(113) “Homogeneous rhodium(I)-catalysis in de novo heterocycle syntheses”, James D. Neuhaus and Michael C. Willis, Org. Biomol. Chem. 2016, 14, 4986–5000 (doi: 10.1039/C6OB00835F)


(112) “Direct synthesis of highly substituted pyrroles and dihydropyrroles using linear selective hydroacylation reactions”, Manjeet K. Majhail, Paul M. Ylioja and Michael C. Willis, Chem. Eur. J. 2016, 22, 7879–7884. (doi: 10.1002/chem.201600311)


(111) “1,4-Disulfino-1,4-diazabicyclo [2.2.2]octane, bis(inner salt)”, Alex. S. Deeming and Michael C. Willis, eEROS, Encyclopedia of Reagents for Organic Synthesis, Wiley, 2016. (doi: 10.1002/047084289X.rn01912)


(110) “One-Pot Sulfoxide Synthesis Exploiting a Sulfinyl-Dication Equivalent Generated from a DABSO/Trimethylsilyl Chloride Sequence”, Danny C. Lenstra, Vincent Vedovato, Emmanuel Ferrer Flegeau, Jonathan Maydom and Michael C. Willis, Org. Lett. 2016, 18, 2086–2089. (doi: 10.1021/acs.orglett.6b00712)


(109) “Heterocycle-derived beta-S-enals as bifunctional linchpins for the catalytic synthesis of saturated heterocycles”, Jingze Niu and Michael C. Willis, Org. Chem. Front. 2016, 3, 625–629. (doi: 10.1039/ c6qo00057f).


(108) “Diversely Substituted Quinolines via Rhodium-Catalyzed Alkyne Hydroacylation”, James D. Neuhaus, Sarah M. Morrow, Michael Brunavs, Michael C. Willis, Org. Lett. 2016, 18, 1562–1565. (doi: 10.1021/acs.orglett.6b00390).


(107) “alpha-Amino Aldehydes as Readily Available Chiral Aldehydes for Rh-Catalyzed Alkyne Hydroacylation”, Joel F. Hooper,  Sangwon Seo, Fiona R. Truscott, James D. Neuhaus and Michael C. Willis, J. Am. Chem. Soc. 2016, 138, 1630–1634. (doi: 10.1021/jacs.5b11892)


(106) “Palladium(II)-Catalyzed Synthesis of Sulfinates from Boronic Acids and DABSO: A Redox-Neutral, Phosphine-Free Transformation”, Alex S. Deeming, Claire J.  Russell and Michael C. Willis, Angew. Chemie. Int. Ed. 2016, 55, 747–750. (doi: 10.1002/anie.201508370R2)


(105) “One-Pot Sulfonamide Synthesis Exploiting the Palladium-Catalyzed Sulfination of Aryl Iodides” Emmanuel Ferrer Flegeau, Jack M. Harrison and Michael C. Willis, Synlett, 2016, 27, 101-102. (open access, doi: 10.1055/s-0035-1560578).


(104) “An Aryne-Based Route to Substituted Benzoisothiazoles”, Yiding Chen and Michael C. Willis, Org. Lett. 2015, 17, 4786-4789. (open access, doi: 10.1021/acs.orglett.5b02347)


(103) “Well-Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes”, Amparo Prades, Maitane Fernández, Sebastian D. Pike, Michael C. Willis and Andrew S. Weller, Angew. Chem. int. Ed. 2015, 54, 8520 –8524. (open access, doi: 10.1002/anie.201503208)


(102) “The Development and Application of Sulfur Dioxide Surrogates in Synthetic Organic Chemistry”, Edward J. Emmett and Michael C. Willis, Asian J. Org. Chem. 2015, 4, 602-611. (open access, doi: 10.1002/ajoc.201500103)


(101) “Rh–POP Pincer Xantphos Complexes for C–S and C–H Activation. Implications for Carbothiolation Catalysis”, Peng Ren, Sebastian D. Pike, Indrek Pernik, Andrew S. Weller* and Michael C. Willis, Organometallics 2015, 34, 711–723. (open access, doi: 10.1021/om500984y)


(100) “The First Stereoselective Synthesis of a Dithiane Derivative of the C18 β-Diketodiene System Proposed for an Active Compound Isolated from Cantharellus cibarius (Chanterelle)”, Jacek Grodner, W. Marek Gołębiewski,* Michael C. Willis, James D. Osborne and Mirosław Gucma, Synthesis 2015, 47, 1181–1189. (doi: 10.1055/s-0034-1379984)


(99) “Combining Organometallic Reagents, the Sulfur Dioxide Surrogate DABSO and Amines: A One-Pot Preparation of Sulfonamides, Amenable to Array Synthesis”, Alex S. Deeming, Claire J.  Russell and Michael C. Willis, Angew. Chemie. Int. Ed. 2014, 53, 1168–1171. (open access, doi: 10.1002/anie.201409283)


(98) “Rediscovering the chemistry of sulfur dioxide: New developments in synthesis and catalysis”, Alex S. Deeming, Edward J. Emmett, Charlotte S. Richards-Taylor and Michael C. Willis, Synthesis, 2014, 46, 2701–2710. (doi: 10.1055/s-0034-1379042)


(97) “Palladium-catalyzed synthesis of ammonium sulfinates from aryl halides and the sulfur dioxide-Surrogate DABSO: A gas and reductant free process”, Edward J. Emmett, Barry R. Hayter and Michael C. Willis, Angew. Chemie. Int. Ed. 2014, 53, 10204–10208. (open access, doi: 10.1002/anie.201404527)


(96) “DABCO-bis(sulfur dioxide), DABSO, as an easy-to-handle source of SO2: Sulfonamide preparation”, Edward J. Emmett and Michael C. Willis, Org. Synth. 2014, 91, 125-136. (doi: 10.15227/orgsyn.091.0125)


(95) Michael C. Willis, Hydroacylation of Alkenes, Alkynes and Allenes. In: Gary A. Molander and Paul Knochel (eds.), Comprehensive Organic Synthesis, 2nd Edition, Vol 4, Oxford: Elsevier; 2014, pp. 961- 994. (doi: 10.1016/B978-0-08-097742-3.00423-7)


(94) “DABSO-Based, Three-Component, One-Pot Sulfone Synthesis”, Alex S. Deeming, Claire J. Russell, Alan J. Hennessy and Michael C. Willis, Org. Lett. 2014, 16, 150-153. (open access, doi: 10.1021/ol403122a)


(93) “2-Aminobenzaldehydes as Versatile Substrates for Rhodium-Catalyzed Alkyne Hydroacylation: Application to Dihydroquinolone Synthesis”, Matthias Castaing, Sacha L. Wason, Beatriz Estepa, Joel F. Hooper and Michael C. Willis, Angew. Chemie. Int. Ed. 2013, 52, 13280–13283. (open access; doi: 10.1002/anie.201308127)


(92) “One-pot three-component sulfone synthesis exploiting palladium-catalysed aryl halide aminosulfonylation”, Charlotte S. Richards-Taylor, David C. Blakemore and Michael C. Willis, Chem. Sci. 2014, 5, 222–228. (open access; doi: 10.1039/C3SC52332B)


(91) “Palladium-Catalyzed Three-Component Diaryl Sulfone Synthesis Exploiting the Sulfur Dioxide Surrogate DABSO”, Edward J. Emmett, Barry R. Hayter and Michael C. Willis, Angew. Chemie. Int. Ed. 2013, 52, 12679–12683. (open access; doi:10.1002/anie.201305369). SynFacts 2014, 10, 117.


(90) “Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines”, Milan Arambasic, Joel F. Hooper and Michael C. Willis, Org. Lett. 2013, 15, 5162-5165. (open access; doi: 10.1021/ol402650q)


(89) “Synthesis of Aromatic Benzo-Fused Five- and Six-Membered Heterocycles via Palladium- and Copper-Catalysed C-X Bond Forming Reactions”, Catherine J. Ball and Michael C. Willis, in Transition-Metal-Mediated Aromatic Ring Construction, Ken Tanaka, Editor, Wiley, 2013. (ISBN: 978-1-118-14892-1)


(88) “3-(Methylthio)propionaldehyde/Methional”, Fiona Truscott and Michael C. Willis, in Encyclopedia of Reagents for Organic Synthesis [Online], 2013, John Wiley & Sons Ltd. (doi: 10.1002/047084289X.rn01527)


(87) “Carbon-carbon bond construction using boronic acids and aryl methyl sulfides: Orthogonal reactivity in Suzuki-type couplings”, Joel F. Hooper, Rowan D. Young, Indrek Pernik, Andrew S. Weller and Michael C. Willis, Chem. Sci. 2013, 4, 1568 1572. (doi: 10.1039/C3SC00052D). SynFacts 2013, 9, 495.


(86) “Traceless Chelation-Controlled Rhodium-Catalyzed Intermolecular Alkene and Alkyne Hydroacylation”, Joel F. Hooper, Rowan D. Young, Andrew S. Weller and Michael C. Willis, Chem. – Eur. J. 2013, 19, 3125 – 3130. (doi: 10.1002/chem.201204056)


(85) “Cascade Palladium- and Copper-Catalyzed Aromatic Heterocycle Synthesis: the Emergence of General Precursors”, Catherine J. Ball, and Michael C. Willis, Eur. J. Org. Chem. 2013, 425 - 441. (doi: 10.1002/ejoc.201201386)


(84) “Catalytic Enantioselective Desymmetrization as a Tool for the Synthesis of Hodgkinsine and Hodgkinsine B”, Robert H. Snell, Matthew J. Durbin, Robert L. Woodward and Michael C. Willis, Chem. – Eur. J. 2012, 18, 16754 - 16764. (doi:10.1002/chem.201203150)


(83) “Exploring small bite–angle ligands for the rhodium–catalyzed intermolecular hydroacylation of betaS–substituted aldehydes with 1–octene and 1–octyne”, Indrek Pernik, Joel F. Hooper, Adrian B. Chaplin, Andrew S. Weller* and Michael C. Willis, ACS Catalysis, 2012, 2, 2779 - 2786. (doi: 10.1021/cs300541m)


(82) “Tandem inverse-electron-demand hetero/retro Diels-Alder reactions for aromatic nitrogen heterocycle synthesis”, Radleigh A. A. Foster and Michael C. Willis, Chem. Soc. Rev. 2013, 42, 63 - 76. (doi: 10.1039/C2CS35316D)


(81) “Palladium-Catalyzed Synthesis of Benzimidazoles and Quinazolinones from Common Precursors”, Jessie E.R. Sadig, Radleigh Foster, Florian Wakenhut and Michael C. Willis, J. Org. Chem. 2012, 77, 9473 - 9486. (doi: 10.1021/jo301805d). Selected by the Editors as a “Feature Article”. SynFacts 2013, 9, 147.


(80) “Intermolecular Alkyne Hydroacylation. Mechanistic Insight from the Isolation of the Vinyl Intermediate that Precedes Reductive Elimination”, Rebekah Pawley, Miguel Huertos, Guy Lloyd–Jones, Andrew S. Weller*, Michael C. Willis, Organometallics 2012, 31, 5650-5659. (doi: 10.1021/om300647n)


(79) “Rhodium-Catalysed Linear-Selective Alkyne Hydroacylation”, Sarah-Jane Poingdestre, Jonathan D. Goodacre, Andrew S. Weller and Michael C. Willis, Chem. Commun. 2012, 48, 6354-6356. (doi: 10.1039/C2CC32713A)


(78) “Copper-Catalyzed Tandem C-N Bond Formation: An Efficient Annulative Synthesis of Functionalised Cinnolines”, Catherine J. Ball, Jeremy Gilmore and Michael C. Willis, Angew. Chemie Int. Ed. 2012, 51, 5718-5722. (doi: 10.1002/anie.201201529). SynFacts 2012, 8, 833.


(77) “Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: Scope of the three-component synthesis of N-aminosulfonamides”, Edward J. Emmett, Charlotte S. Richards-Taylor, Bao Nguyen, Alfonso Garcia-Rubia, Barry R. Hayter and Michael C. Willis, Org. Biomol. Chem. 2012, 10, 4007 - 4014. (doi; 10.1039/C2OB07034K). Featured on the front cover of the journal.


(76) “Intermolecular hydroacylation: High Activity Rhodium Catalysts Containing Small Bite Angle Diphosphine Ligands.” Adrian B. Chaplin, Joel F. Hooper, Andrew S. Weller and Michael C. Willis, J. Am. Chem. Soc. 2012, 134, 4885-4897. (doi: 10.1021/ja211649a)


(75) “Palladium-Catalyzed Direct Functionalization of Benzoxazoles with Alkenyl Iodides”, Maria Gerelle, Anne J. Dalencon, Michael C. Willis, Tetrahedron Lett. 2012, 53, 1954-1957. (doi: 10.1016/j.tetlet.2012.02.014)


(74) “Aryl Methyl Sulfides as Substrates for Rhodium-Catalyzed Alkyne Carbothiolation: Arene Functionalization with Activating Group Recycling”, Joel F. Hooper, Adrian B. Chaplin, Carlos González-Rodríguez, Amber L. Thompson, Andrew S. Weller and Michael C. Willis, J. Am. Chem. Soc. 2012, 134, 2906 - 2909. (doi: 10.1021/ja2108992). SynFacts 2012, 8, 534.


(73) “Author Profile”, Angew. Chem. Int. Ed. 2012, 51, 1304. (doi: 10.1002/anie.201107516).


(72) “Exploring (Ph2PCH2CH2)2E Ligand Space (E = O, S, PPh) in Rh(I) Alkene Complexes as Potential Hydroacylation Catalysts”, S. D. Pike, R. J. Pawley, A. B. Chaplin, A. L. Thompson, J. A. Hooper, M. C. Willis and A.S. Weller* Eur. J. Inorg. Chem. 2011, 5558 - 5565. (doi: 10.1002/ejic.201100958).


(71) “An Alkyne Hydroacylation Route to Highly Substituted Furans”, Philip Lenden, David A. Entwistle and Michael C. Willis, Angew. Chem. Ind. Ed. 2011, 50, 10657–10660. (doi: 10.1002/anie.201105795). Selected by the Editors as a “Hot” article. Highlighted in Synfacts (2012, page 135).


(70) “DABCO-Bis(sulfur dioxide), DABSO, as a Convenient Source of Sulfur Dioxide for Organic Synthesis: Utility in Sulfonamide and Sulfamide Preparation”, Holly Woolven, Carlos González-Rodríguez, Isabel Marco, Amber L. Thompson and Michael C. Willis, Org. Lett. 2011, 13, 4876–4878. (doi: 10.1021/ol201957n)


(69) “Catalytic Enantioselective Total Synthesis of Hodgkinsine B”, Robert H. Snell, Robert L. Woodward and Michael C. Willis, Angew. Chem Int. Ed. 2011, 50, 9116-9119. (doi: 10.1002/anie.201103864)


(68) “Replacing Dichloroethane as a Solvent for Rhodium-Catalysed Intermolecular Alkyne Hydroacylation Reactions: The Utility of Propylene Carbonate”, Philip Lenden, Paul M. Ylioja, Carlos González-Rodríguez, David A. Entwistle and Michael C. Willis, Green Chem. 2011, 13, 1980-1982. (doi: 10.1039/C1GC15293A)


(67) “Rhodium-Catalyzed Branched-Selective Alkyne Hydroacylation: A Ligand Controlled Regioselectivity Switch”, Carlos González-Rodríguez, Rebekah J. Pawley, Adrian B. Chaplin, Amber L. Thompson, Andrew S. Weller and Michael C. Willis, Angew. Chemie Int. Ed. 2011, 50, 5134 –5138. (doi: 10.1002/anie.201100956)


(66) “O-Substituted Alkyl Aldehydes for Rhodium-Catalyzed Intermolecular Alkyne Hydroacylation: The Utility of Methylthiomethyl-Ethers”, Scott R. Parsons, Joel F. Hooper and Michael C. Willis, Org. Lett. 2011, 13, 998-1000. (doi: 10.1021/ol1030662)


(65) “Rhodium-Catalyzed Enantioselective Intermolecular Hydroacylation Reactions”, Carlos González-Rodríguez and Michael C. Willis, Pure and Applied Chemistry 2011, 85, 577- 585. (doi: 10.1351/PAC-CON-10-09-23)


(64) “Palladium-Catalyzed Aminosulfonylation of Aryl Halides”, Bao Nguyen, Edward J. Emmett and Michael C. Willis, J. Am. Chem. Soc. 2010, 132, 16372–16373. (doi: 10.1021/ja1081124)


(63) “Palladium- and Copper-Catalyzed Aryl Halide Amination, Etherification and Thioetherification Reactions in the Synthesis of Aromatic Heterocycles”, Jessie E. R. Sadig and Michael C. Willis, Synthesis 2011, 1 - 22. (doi: 10.1055/s-0030-1258294)


(62) “Cascade Palladium-Catalyzed Direct Intramolecular Arylation/Alkene Isomerization Sequences: Synthesis of Indoles and Benzofurans”, Myriam Yagoubi, Ana C. F. Cruz, Paula L. Nichols, Richard L. Elliott and Michael C. Willis, Angew. Chem. Int. Ed. 2010, 49, 7958 – 7962. (doi: 10.1002/anie.201004097). Selected by the Editors as a “Hot” article.


(61) “Rhodium-Catalyzed Intermolecular Alkyne Hydroacylation: The Enantioselective Synthesis of alpha- and beta-Substituted Ketones via Kinetic Resolution”, Carlos González-Rodríguez, Scott R. Parsons, Amber L. Thompson and Michael C. Willis, Chem. Eur. J. 2010, 16, 10950 – 10954. (doi: 10.1002/chem.201001748)


(60)“Palladium Catalyzed Tandem Alkenyl- and Aryl-C-N Bond Formation:  A Cascade N-Annulation Route to 4-, 5-, 6- and 7-Chloro-Indoles” Luke C. Henderson, Matthew J. Lindon and Michael C. Willis, Tetrahedron 2010, 66, 6632-6638. (doi: 10.1016/ j.tet2010.05.046) [Invited contribution to Symposium-in-Print in honour or Prof. S. V. Ley receiving the 2010 Tetrahedron prize]


(59)“Catalytic Intramolecular Ketone Hydroacylation: Enantioselective Phthalide Synthesis” (Highlight article), Michael C. Willis, Angew. Chem. Int. Ed. 2010, 49, 6026-6027.(doi: 10.1002/anie.201000159)


(58) “Controlling Selectivity in Intermolecular Alkene or Aldehyde Hydroacylation Reactions Catalysed by {Rh(L2)}+ Fragments”, Rebekah J. Pawley, Gemma L. Moxham, Romaeo Dallanegra, Adrian B. Chaplin, Simon K. Brayshaw, Andrew S. Weller and Michael C. Willis, Organometallics 2010, 29, 1717-1728.


(57) “Enantioselective Desymmetrizing Palladium Catalyzed Carbonylation Reactions:  The Catalytic Asymmetric Synthesis of Quaternary Carbon Center Containing 1,3-Dienes”, Simon J. Byrne, Anthony J. Fletcher, Paul Hebeisen and Michael C. Willis, Org. Biomol. Chem. 2010, 8, 758-760.


(56) “Transition Metal Catalyzed Alkene and Alkyne Hydroacylation”, M. C. Willis, Chem. Rev. 2010, 110, 725-748.


(55) “Palladium-Catalyzed Aryl-Carbonylation – Intramolecular O-Enolate Acylation: Efficient Isocoumarin Synthesis”, Andrew C. Tadd, Mark R. Fielding and Michael C. Willis, Chem. Commun. 2009, 6744–6746.


(54) “Modern Applications of Transition Metal Catalysis in Heterocycle Synthesis”, Michael C. Willis, Tetrahedron 2009, 65, 8907. Editorial for Tetrahedron-Symposium-in-Print.


(53) “Palladium Catalyzed Tandem Alkenyl- and Aryl-C-N Bond Formation:  A Cascade N-Annulation Route to 1-Functionalised 7-Azaindoles”, Roy C. Hodgkinson, Jurgen Schulz and Michael C. Willis, Tetrahedron 2009, 65, 8940-8949. [Invited contribution to Symposium-in-Print on Modern Applications of Transition Metal Catalysis in Heterocycle Synthesis]


(52) “Changing the Local Coordination Environment in Mono- and Bi- Nuclear Lanthanide Complexes through Click Chemistry”, Maite Jauregui, William S. Perry, Clémence Allain, Lewis R. Vidler, Michael C. Willis, Alan M. Kenwright, John S. Snaith, Graeme J. Stasiuk, Mark P. Lowe and Stephen Faulkner, Dalton Trans. 2009, 6283-6285.


(51) “Intermolecular Rhodium Catalyzed Hydroacylation of Allenes: The Regioselective Synthesis of α,β-Unsaturated Ketones”, Helen E. Randell-Sly, James D. Osborne, Robert L. Woodward, Gordon S. Currie and Michael C. Willis, Tetrahedron 2009, 65, 5110–5117. [Invited contribution to Prof. M. Krische’s Tetrahedron young investigator award issue]


(50) “Direct Catalytic Diastereoselective Mannich Reactions: The Synthesis of Protected β-Hydroxy-α-Aminoketones”, Nikki E. Stainforth, Gary A. Cutting, Matthew P. John and Michael C. Willis, Tetrahedron: Asymmetry 2009, 20, 741-743. [Invited contribution to Prof. G. W. Fleet celebratory 65th birthday issue]


(49) “Total Synthesis of Rapamycin”, Steven V. Ley, Miles N. Tackett, Matthew L. Maddess, James C. Anderson, Paul E. Brennan, Michael W. Cappi, Jag P. Heer, Coline Helgen, Masakuni Kori, Cyrille Kouklovsky, Stephen P. Marsden, Joanne Norman, David P. Osborn, María Palomero, John B. J. Pavey, Catherine Pinel, Lesley A. Robinson, Jürgen Schnaubelt, James S. Scott, Christopher D. Spilling, Hidenori Watanabe, Kieron E. Wesson, and Michael C. Willis, Chem. Eur. J. 2009, 15, 2874 – 2914.


(48) “Cascade Palladium-Catalyzed Alkenyl Aminocarbonylation/Intramolecular Aryl Amidation: An Annulative Synthesis of 2-Quinolones”, A. C. Tadd, A. Matsuno, M. R. Fielding and M. C. Willis, Org. Lett. 2009, 11, 583–586. [Highlighted in Synfacts; Synfacts 2009, 5, 482.]


(47) “Tandem Copper-Catalysed Aryl and Alkenyl Amination Reactions: The Synthesis of N-Functionalised Indoles”, R. C. Hodgkinson, J. Schulz and M. C. Willis, Org. Biomol. Chem. 2009, 7, 232-234.


(46) “Catalytic Enantioselective Intermolecular Hydroacylation: Rhodium-Catalyzed Combination of β-S-Aldehydes and 1,3-Disubstituted Allenes”, J.D. Osborne, H. E. Randell-Sly, G. S. Currie, A. R. Cowley M. C. Willis, J. Am. Chem. Soc. 2008, 130, 17232–17233. [Highlighted in Synfacts; Synfacts 2009, 3, 289.]


(45) “Rhodium-Catalysed Hydroacylation or Reductive Aldol Reactions: A Ligand Dependent Switch of Reactivity”, J. D. Osborne and M. C. Willis, Chem. Commun. 2008, 5025-5027.


(44) “Intermolecular Alkene Hydroacylation using β-S-Substituted Aldehydes. Mechanistic Insight into the Role of a Hemilabile P-O-P Ligand”, G. L. Moxham, H. Randell-Sly, S. K. Brayshaw, A. S. Weller and M. C. Willis, Chem. Eur. J., 2008, 14, 8383-839.


(43) “Palladium-Catalyzed -Arylation of Oxindoles”, M. J. Durbin and M. C. Willis, Org. Lett. 2008, 10, 1413-1415. [Highlighted in Synfacts; Synfacts 2008, 6, 632.]


(42) “Intramolecular Palladium-Catalyzed Direct Arylation of Alkenyl Triflates”, A. C. F. Cruz, N. D. Miller and M. C. Willis, Org. Lett. 2007, 9, 4391-4393.


(41) “Palladium-Catalysed N-Annulation Routes to Indoles: The Synthesis of Indoles with Sterically Demanding N-Substituents, Including Demethylasterriquinone A1”, A. J. Fletcher, M. N. Bax and M. C. Willis, Chem. Commun. 2007, 4764 - 4766.


(40) “Copper-Catalysed Benzofuran Synthesis: Developing Aryl Bromide-Alkenyl Triflates as General Heterocycle Precursors”, A. C. Tadd, M. R. Fielding and M. C. Willis, Tetrahedron Lett. 2007, 48, 7578-7581.


(39) “Site-Selective Modification Of Peptides Using Rhodium and Palladium Catalysis: Complementary Electrophilic and Nucleophilic Arylation”, C. J. Chapmam, A. Matsuno, C. G. Frost and M. C. Willis, Chem. Commun. 2007, 3903-3905.


(38) “Direct Catalytic Enantioselective Mannich Reactions:  Synthesis of Protected Anti-α,β-Diamino Acids”, G. A. Cutting, N. E. Stainforth, M. P. John, G. Kociok-Köhn and M. C. Willis, J. Am. Chem. Soc. 2007, 129, 10632-10633.


(37) “Palladium catalysed couplings of ammonia and hydroxide with aryl halides: The direct synthesis of primary anilines and phenols”, M. C. Willis, Angew. Chem. Int. Ed. 2007, 46, 3402-3404.


(36) “A Second Generation Catalyst for Intermolecular Alkene and Alkyne Hydroacylation using β-S-Substituted Aldehydes: The Role of a Hemilabile P-O-P Ligand”, G. L. Moxham, H. E. Randell-Sly, S. K. Brayshaw, R. L. Woodward, A. S. Weller, M. C. Willis, Angew. Chem. Int. Ed. 2006, 45, 7618.


(35) “Tandem Palladium Catalysed Urea Arylation – Intramolecular Ester Amidation: Regioselective Synthesis of 3-Alkylated 2,4-Quinazolinediones”, M. C. Willis, R. H. Snell, A. J. Fletcher and R. L. Woodward, Org. Lett. 2006, 8, 5089-5091.


(34) “Chelating Phosphine Boranes as Hemilabile Ligands. Synthesis of [Mn(CO)32-H3B·dppm)][BArF4] and [Mn(CO)41-H3B·dppm)][BArF4]”, N. Merle, C. G. Frost, G. Kociok-Köhn, M. C. Willis and A. S. Weller, Eur. J. Inorg. Chem. 2006, 4068-4073.


(33) “Rhodium Catalysed Intermolecular Chelation Controlled Alkene and Alkyne Hydroacylation: Synthetic Scope of β-S-Substituted Aldehyde Substrates”, M. C. Willis, H. E. Randell-Sly, R. L. Woodward, S. J. McNally and G. S. Currie, J. Org. Chem. 2006, 71, 5291-5297.


(32) “Palladium Catalysed Intramolecular Enolate O-Arylation and Thio-enolate S Arylation: Synthesis of Benz[b]furans and Benzo[b]thiophenes”, M. C. Willis, D. Taylor and A. T. Gillmore, Tetrahedron 2006, 62, 11513-11520. (invited contribution; Young Investigator Prize, Symposium-in-Print).


(31) “Aryl-Alkenyl-Dihalides as Substrates for Palladium Catalysed Tandem C-N Bond Formation: Efficient Synthesis of 1-Functionalised Indoles”, M. C. Willis, G. N. Brace, T. J. K. Findlay and I. P. Holmes, Adv. Syn. Catal. 2006, 348, 851-856.


(30) “Rhodium-Catalyzed Reductive Aldol Reactions Using Aldehydes as the Stoichiometric Reductants”, M. C. Willis and R. L. Woodward, J. Am. Chem. Soc. 2005, 127, 18012-18013.


(29) “Efficient Palladium-Catalysed Enamide Synthesis From Enol Triflates and Enol Tosylates”, M. C. Willis, G. N. Brace and I. P. Holmes, Synthesis, 2005, 3229-3234.


(28) “A New Reactivity Pattern for Vinyl Bromides; Cine-Substitution via Palladium Catalysed C-N Coupling/Michael Addition Reactions”, M. C. Willis, J. Chauhan and W. G. Whittingham, Org. Biomol. Chem. 2005, 3, 3094-3095.


(27) “Ruthenium(II) Complexes of the Chelating Phosphine Borane H2ClB·dppm”, N. Merle,C. G. Frost, G. Kociok Köhn, M. C. Willis and A. S. Weller, J. Organometallic Chem. 2005, 690, 2829-2834.


(26) “Chelation Controlled Intermolecular Alkene and Alkyne Hydroacylation: The Utility of β-Thioacetal Aldehydes”, M. C. Willis, H. E. Randell-Sly, R. L. Woodward and G. S. Currie, Org. Lett. 2005, 7, 2249-2251.


(25) “The Direct Catalytic Enantioselective Synthesis of Protected Aryl β-Hydroxy-α-Amino Acids”, M. C. Willis, G. A. Cutting, V. J.-D. Piccio, M. J. Durbin and M. P. John, Angew. Chem. Int. Ed. 2005, 44. 1543-1545.


(24) “Palladium Catalysed Tandem Alkenyl- and Aryl-C-N Bond Formation:  A Cascade N-Annulation Route to 1-Functionalised Indoles”, M. C. Willis, G. N. Brace and I. P. Holmes, Angew. Chem. Int. Ed. 2005, 44, 403-406.


(23) “Palladium Catalysed Intramolecular O-Arylation of Enolates: Application to Benzo[b]furan Synthesis”, M. C. Willis, D. Taylor and A. T. Gillmore, Org. Lett. 2004, 6, 4755-4757.


(22) “Transition Metal Complexes of the Chelating Phosphine Borane Ligand Ph2PCH2Ph2P·BH3”, N. Merle, G. Koicok-Köhn, M. F. Mahon, C. G. Frost, G. D. Ruggerio, A. S. Weller and M. C. Willis, J. Chem. Soc., Dalton Trans. 2004, 3883-3892.


(21) “A Direct Catalytic and Diastereoselective Aldol Route to Protected α,β-Dihydroxy-Ketones”, M. C. Willis, G. A. Cutting and M. P. John, Synlett 2004, 1195-1198.


(20) “Automated Structure Elucidation of two Unexpected Products in a Reaction of an α,β-Unsaturated pyruvate”, G. J. Sharman, I. C. Jones, M. P. Parnell, M. C. Willis, M. F. Mahon, D. V. Carlson, A. Williams, M. Elyashberg, K. Blinov and S. G. Molodstov, J. Magn. Reson. Chem. 2004, 42, 567-572.


(19) “Enantioselective Suzuki Reactions:  The Catalytic Asymmetric Synthesis of Compounds Containing Quaternary Carbon Centers”,  M. C. Willis, L. H. W. Powell,  C. K. Claverie and S. J. Watson, Angew. Chem. Int. Ed. 2004, 42, 1249-1251.


(18) “Chelation Controlled Intermolecular Hydroacylation:  The Direct Addition of Alkyl Aldehydes to Functionalised Alkenes”, M. C. Willis, S. J. McNally and P. J. Beswick, Angew. Chem. Int. Ed. 2004, 42, 340-343.


(17) “Palladium Catalysed Aryl Enol Ether Synthesis from Vinyl Triflates”, M. C. Willis, D. Taylor and A. T. Gillmore, Chem. Commun. 2003, 2222-2223.


(16) “One-Pot Synthesis of Perhydrofuro[2,3-b]pyran Derivatives”, M. C. Willis and S. E. Flower, Synlett 2003, 1491-1493.


(15) “Diphosphine Mono-Sulfides: Readily Available Chiral Monophosphines”, C. J. Chapman, C. G. Frost, M. P. Gill-Carey, G. Kociok-Köhn, M. F. Mahon, A. S. Weller and M. C. Willis, Tetrahedron: Asym. 2003, 14, 705-710.


(14) “Palladium Catalysed Enamine Synthesis from Vinyl Triflates”, M. C. Willis and G. N. Brace, Tetrahedron Lett. 2002, 43, 9085-9088.


(13) “A Direct Catalytic Aldol Route to Protected β-Hydroxy-α-Amino Acids” M. C. Willis and V. J.-D. Piccio, Synlett 2002, 1625-1628.


(12) “Tandem Intermolecular Suzuki Coupling, Intramolecular Vinyl Triflate–Arene Coupling”, M. C. Willis, C. K. Claverie and M. F. Mahon, Chem. Commun. 2002, 832-833.


(11) “Intermolecular Hydroacylation of Acrylate Esters: A New Route to 1,4-Dicarbonyls”, M. C. Willis and S. Sapmaz, Chem. Commun. 2001, 2558-2559.


(10) “The Preparation and Suzuki Coupling Reactivity of Cyclic 1,3-Dione Derived Mono- and Ditriflates”, M. C. Willis and C. K. Claverie, Tetrahedron Lett. 2001, 42, 5105-5107.


(9) “Chelating Mono-Borane Phosphines: Rational and High-Yield Synthesis of [(COD)Rh-{((eta)2BH3)Ph2PCH2PPh2}][PF6]”, M. Ingleson, N. J. Patmore, G. D. Ruggiero, C. G. Frost, M. F. Mahon, M. C. Willis and A. S. Weller, Organometallics 2001, 21, 4434-4436.


(8) “Enantioselective Cycloaddition Reactions” in Rodd’s Chemistry of Carbon Compounds: Topical Volumes, Asymmetric Catalysis, M. Sainsbury, Ed., Elsevier, Oxford, 2001.


(7) “Enantioselective and Diastereoselective Mukaiyama-Michael Reactions Catalysed by Bis(oxazoline) Copper(II) Complexes”, D. A. Evans, K. A. Scheidt, J. S. Johnston and M. C. Willis, J. Am. Chem. Soc. 2001, 123, 4480-4491.


(6) “Organic Aspects of Organometallic Chemistry”, M. C. Willis and Christopher G. Frost, Organometallic Chemistry Specialist Periodical Report 1999, Volume 29, M. Green, Ed., Royal Society of Chemistry.


(5) “Catalytic Enantioselective Michael Additions to Unsaturated Ester Derivatives Using Chiral Copper(II) Lewis Acid Complexes”, D. A. Evans, M. C. Willis and J. S. Johnston, Org. Lett. 1999, 1, 865-868.


(4) “Enantioselective Desymmetrisation”, M. C. Willis, J. Chem Soc., Perkin Trans. 1 1999, 1765-1784.


(3) “Organic Aspects of Organometallic Chemistry”, M. C. Willis and Christopher G. Frost, Organometallic Chemistry Specialist Periodical Report 1998, Volume 28, M. Green, Ed., Royal Society of Chemistry.


(2) “(Phenylsulfonyl)-trimethylsilylmethane”, Steven V. Ley, M. C. Willis, in “Encyclopedia of Reagents for Organic Synthesis”, L. Paquette, Ed, J. Wiley: Chichester, 1995, Vol. 6, 4061.


(1) “An Improved Procedure for the N-Formylation of Secondary Amines Using  Chlorotrimethylsilane-Imidazole-N,N-Dimethylformamide”; M. B. Berry, J. Blagg, D. Craig, M. C. Willis, Synlett 1992, 659-660.


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